Dr Brian Chung Hon-yin is a Clinical Associate Professor at Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, the University of Hong Kong. Specialized in clinical genetics and genomics, Dr Chung is interested in research fields including medical application of whole genome technologies, clinical genetics, genetic counselling, precision medicine and multi-omics. He is currently the President of Asia Pacific Society of Human Genetics. Dr Chung also acts as Chief Medical and Scientific Officer at Hong Kong Genome Institute to promote the city’s long-term development of genomic medicine by driving clinical application, advancing research, nurturing talents and enhancing public literacy.

From Genomics to Clinic: The Role of the Hong Kong Genome Project in Transforming Patient Care and Population Health

The biotechnology revolution is transforming medicine by bringing genomic innovation from the research laboratory into real-life clinical practice. Genomic medicine, powered by large-scale sequencing and integrated analysis, is redefining how diseases are diagnosed, prevented, and treated worldwide. The Hong Kong Genome Project (HKGP) is a leading example of this transformation in action. Implemented by the Hong Kong Genome Institute (HKGI), HKGP could integrate whole genome sequencing (WGS) into healthcare to uncover genetic causes of undiagnosed diseases, guide early detection for at-risk individuals and families, and inform reproductive and precision treatment decisions. By linking cutting-edge biotechnology with hospitals, clinicians, and patients, HKGP demonstrates how scientific expertise and clinical application converge—turning breakthrough discoveries into actionable medical insights that improve health outcomes and advance precision medicine in Hong Kong and beyond.